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. 2020 Aug 26;105(12):e4778–e4791. doi: 10.1210/clinem/dgaa591

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Figure 2. — Among trial participants who were overweight at randomization, greater reductions in body mass index (BMI) and hemoglobin A1c (HbA1C) over follow-up were associated with better digit symbol coding (DSC) score at follow-up, and greater increase in physical activity (PA) over follow-up was associated with better cognitive composite score. However, these associations were not significant among participants who were obese at randomization (interaction P-values: 0.010, 0.023, 0.031). Raw values are presented with unadjusted slopes for each group.