Table 4.
Levels of physiological markers at the time of randomization, and change in those markers between randomization and the visit prior to the first cognitive assessment, among participants who received 2 or 3 cognitive assessments
| Diabetes Marker | Baseline | Change Over Follow-up | |||||
|---|---|---|---|---|---|---|---|
| Overall | DSE | ILI | Overall | DSE | ILI | ||
| BMI (kg/m2)a | Mean (95% CI) | 35.75 (35.41, 36.10) | 35.92 (35.44, 36.40) | 35.59 (35.10, 36.09) | -4.69 (-5.14, -4.24) | -2.20 (-2.79, -1.60) | -7.10 (-7.72, -6.49) |
| Median (IQR) | 34.87 (31.44, 39.10) | 35.05 (31.66, 39.14) | 34.75 (31.14, 39.06) | -3.85 (-8.59, 0.17) | -1.48 (-5.78, 2.03) | -6.33 (-11.07, -2.27) | |
| Paffenbarger (kcal/week)b | Mean (95% CI) | 816.68 (743.2, 890.2) | 853.10 (743.3, 962.9) | 780.47 (682.3, 878.6) | 252.51 (190.1, 314.9) | 83.09 (-0.47, 166.7) | 421.00 (331.4, 510.7) |
| Median (IQR) | 448 (84, 1177) | 504 (112, 1183.5) | 420 (56, 1148) | 179.2 (-95.7, 591.4) | 78.6 (-206.4, 378.1) | 296.8 (18.67, 819.2) | |
| Glucose (mg/dL) | Mean (95% CI) | 149.81 (147.2, 152.4) | 149.49 (145.9, 153.1) | 150.13 (146.3, 154.0) | -9.04 (-10.9, -7.14) | -5.44 (-8.06, -2.82) | -12.53 (-15.3, -9.80) |
| Median (IQR) | 140 (120, 170) | 142 (121, 169) | 138.5 (120, 172) | -7.4 (-22.6, 7.6) | -4.1 (-17.2, 10.4) | -11.3 (-25.8, 3.8) | |
| HbA1c, % | Mean (95% CI) | 7.20 (7.13, 7.26) | 7.20 (7.11, 7.30) | 7.19 (7.10, 7.28) | -0.15 (-0.21, -0.10) | -0.07 (-0.14, 0.00) | -0.24 (-0.31, -0.17) |
| Median (IQR) | 7 (6.5, 7.7) | 7 (6.5, 7.7) | 7 (6.4, 7.7) | -0.15 (-0.6, 0.27) | -0.04 (-0.5, 0.37) | -0.21 (-0.69, 0.19) | |
Abbreviations: CI, confidence interval; DSE, Diabetes support and education; HbA1c, hemoglobin A1c; ILI, Intensive lifestyle intervention; IQR, interquartile range.
a BMI change is presented in this table only as percent change in BMI.
b Paffenbarger leisure time physical activity was collected on a subset of individuals.