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Pubertal timing |
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Cryptorchidism/testicular surgery |
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Sexual function and frequency |
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Sexually transmitted infections |
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Infections of prostate or testicle |
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Current and former medications |
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Use of alcohol, tobacco, illicit drugs |
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Systemic disease |
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Environmental exposures, including radiation, pesticides, and occupational |
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Cancer diagnosis and treatment |
Physical examination |
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Presence of sexual hair/Tanner stage |
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Bitemporal hemianopsia (pituitary mass) |
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Reduced testicular volume (<15 cc) |
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Testicular mass |
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Presence of vas deferens bilaterally |
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Presence of varicocele or other scrotal mass |
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Presence of cryptorchidism or hypospadias |
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Synovitis of second and third metacarpal-phalangeal joints, “bronzed” appearance or stigmata of liver disease or heart failure (hemochromatosis) |
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Presence of marked muscle hypertrophy suggesting anabolic steroid use |