Table 1.
N (%) | |
Age (years) | |
Median (range) | 75 (64 to 91) |
Sex | |
Male | 18 (78) |
Female | 5 (22) |
ECOG Performance Status | |
0 | 8 (35) |
1 | 12 (52) |
2 | 3 (13) |
Ethnicity | |
Caucasian | 19 (83) |
Mediterranean | 3 (13) |
Pacific Islander | 1 (4) |
Site of primary tumor | |
Head and neck | 6 (26) |
Upper limb | 5 (22) |
Lower limb | 4 (17) |
Trunk | 1 (4) |
Unknown | 7 (30) |
ICI | |
Avelumab (PD-L1 inhibitor) | 15 (65) |
Pembrolizumab (PD-1 inhibitor) | 5 (22) |
Tislelizumab (PD-1 inhibitor) | 3 (13) |
MCPyV status | |
Positive | 7 (30) |
Negative | 16 (70) |
Presence of visceral disease | 17 (74) |
Prior platinum-based chemotherapy | 10 (43) |
Prior immunosuppression | 2 (9) |
History of autoimmune disease | 2 (9) |
ECOG, Eastern Cooperative Oncology Group; ICI, immune checkpoint inhibitor; MCPyV, Merkel cell polyomavirus.