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. 2020 Aug 28;75(11):2081–2088. doi: 10.1093/gerona/glaa214

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© The Author(s) 2020. Published by Oxford University Press on behalf of The Gerontological Society of America.

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Figure 5. — Apigenin inhibited autophagy and mitochondria-dependent apoptosis in skeletal muscle of aged mice. (A) Representative images and quantification (fold change from Young) were shown for (B) BNIP3, (C) p62, and (D) LC3-II/I. (E) Representative images and quantification (fold change from Young) of cytochrome C in (F) cytosol and (G) mitochondria fractions were shown, respectively. (H) The DNA fragmentation. Activities of (I) PARP (fold change from Young), and (J) caspase 3. Data are presented as the mean ± SD (n = 8–10). *p < .05, versus the Old group (25 months).