Table 5.

Number of patients with bacterial, viral, or any (bacterial and/or viral) potential pathogens detected by MTB and BPFA

Bacteria	MTB	BPFA	Effect Measure	p-value*
Any bacteria, patient No. (%)	182 (66.4%)	207 (75.5%)	OR (95% CI) = 2.09 (1.24,3.59)	0.003
Number of bacterial species per patient
Mean (SD)	0.92 (0.82)	1.35 (1.19)	Diff (95% CI=0.43(0.30,0.56)	<0.001
Median (IQR)	1 (0,1)	1 (1,2)	NA	<0.001
Virus
Any virus, patient No.(%)	111 (40.5%)	167 (60.9%)	OR (95%CI)=9.00(4.12,23.30)	<0.001
Number of virus species per patient
Mean (SD)	0.43 (0.55)	0.68(0.61)	Diff (95%CI)=0.25 (0.18,0.31)	<0.001
Median IQR)	0 (0,1)	1 (0,1)	NA	<0.001
Combined bacteria and virus species
Any pathogen detected, patient No.(%)	224 (80.9%)	251 (90.6%)	OR (95%CI)=3.33 (1.71, 6.98)	<0.001
Number of pathogen species per patient
Mean (SD)	1.35 (0.94)	2.03 (1.27)	Diff (95%CI)=0.68 (0.53,0.83)	<0.001
Median IQR)	1 (1,2)	2 (1,3)	NA	<0.001

MTB = Multi-test bundle; BPFA = BioFire® Pneumonia FilmArray®

^⁎p-value was based on McNemar test for odds ratio, paired t-test for mean difference, and Wilcoxon signed rank test for distribution