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. 2020 Oct 2;5(19):e138215. doi: 10.1172/jci.insight.138215

Figure 2. PPP2R2D expression is increased in T cells from patients with SLE.

Figure 2

(A) The mRNA expression of PPP2R2D and in T cells from healthy subjects (n = 7) or from patients with SLE (n = 19). HC, healthy control. (B) Western blot analysis of the protein expression levels of PPP2R2D and β-actin in T cells from patients with SLE or matched healthy donors. Healthy donor 1 (H1) is age-, sex-, and ethnicity-matched with lupus patient 1 (L1); H2 is age-, sex-, and ethnicity-matched with L2, and so on. (C) Cumulative data for quantification of the level of PPP2R2D in the blots shown in B. Healthy controls (HC), n = 11; SLE patients, n = 11. (D) Pearson correlation analysis showing the relationship between PPP2R2D expression and Systemic Lupus Erythematosus Disease Activity Index (SLEDAI). *P < 0.05 using unpaired t test (A) or paired t test (C).