Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Anti-HIV activity of representative compounds
| Compds | Mean IC50 + SD (nM) |
|
|---|---|---|
| Anti-HIV-1 activity in p24 assay HV-1Ba-L (R5) | CCR5 Ca assay | |
| 1b | 160 ± 40 | 94 |
| 39 | 10 | 28 |
| 40 | 39 ± 34.4 | 13 |
| Zidovudinea | 7 ± 4 | – |
| Nelfinavirb | 12 ± 8 | – |
Zidovudine is a reverse transcriptase inhibitor.
Nerfinavir is a HIV-1 protease inhibitor.
