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. 2020 Oct 16;102:63–69. doi: 10.1016/j.ijid.2020.10.036

Table 1.

Association of variables with seropositivity.

Characteristics Total (N = 478) IgG+ (N = 130) IgG- (N = 348) p OR (95% CI)
Age
 From 20 to 39 230 (48%) 58 (25%) 172 (75%) Ref
 From 40 to 59 196 (41%) 60 (30%) 136 (70%) 0.210 0.76 (0.5−1.16)
 >60 52 (11%) 12 (23%) 40 (77%) 0.740 1.12 (0.55−2.28)



Gender
 Female 329 (69%) 87 (26%) 242 (73%) 0.600 0.9 (0.67,1.24)
 Male 149 (31%) 43 (29%) 106 (31%)



Ethnicity
 Hispanic 132 (28%) 41 (31%) 91 (69%) 0.005 2.42 (1.3−4.5)
 Black 87 (18%) 28 (32%) 59 (68%) 0.006 2.55 (1.3−5.02)
 Asian 114 (24%) 30 (26%) 84 (74%) 0.050 1.9 (1.00−3.69)
 Other race 30 (6%) 13 (43%) 17 (57%) 0.002 4.1 (1.7−9.9)
 Caucasian 115 (24%) 18 (15%) 97 (85%) Ref



Living conditions
 Alone 116 (24%) 30 (25%) 86 (75%) 0.800 0.93 (0.66−1.32)
 With others 362 (76%) 100 (28%) 262 (72%)



Housing
 Apartment/Condo 269 (56%) 83 (31%) 186 (69%) 0.040 1.37 (1.008,1.86)
 Single family home 209 (44%) 47 (23%) 162 (78%)



Means of travel to work
 Private transport 252 (53%) 60 (24%) 192 (76%) Ref
 Public transportb 204 (43%) 59 (29%) 145 (71%) 0.200 1.3 (0.85−1.98)
 Walk to work 22 (4%) 11 (50%) 11 (50%) 0.010 3.2 (1.3−7.75)



Comorbidities
 Hypertension 81 (17%) 25 (31) 56 (69%) 0.400 1.06 (0.9,1.2)
 Diabetes 31 (7%) 10 (32%) 21 (68%) 0.300 1.08 (0.8−1.3)
 Heart failure 2 (0.5%) 1 (50%) 1 (50%) 0.400 1.4 (0.36−5.83)
 Copd/Asthma 46 (10%) 18 (39%) 28 (61%) 0.080 1.21 (0.95−1.54)
 Chronic kidney disease 3 (0.6%) 1 (33%) 2 (67%) 0.600 1.09 (0.49−2.43)
 Cancer 3 (0.6%) 1 (33%) 2 (67%) 0.600 1.09 (0.49−2.43)
 Rheumatological diseases 10 (2%) 4 (40%) 6 (60%) 0.270 1.21 (0.73−2.02)
History of BCG vaccinec 204 (43%) 63 (31%) 141 (69%) 0.120 1.09 (0.97−1.22)



History of symptoms of COVID
 Fever 80 (17%) 62 (78%) 18 (23%) <0.001 3.68 (2.44−5.54)
 Myalgias 128 (27%) 70 (55%) 58 (45%) <0.001 5.84 (3.74,9.11)
 Cough/Sorethroat/Sinusitis 150 (31%) 72 (48%) 78 (52%) <0.001 4.3 (2.8,6.59)
 Ageusia 61 (13%) 53 (87%) 8 (13%) <0.001 29.25 (13.36−64.04)
 Anosmia 65 (14%) 55 (85%) 10 (15%) <0.001 24.79 (12.08−50.86)
 Diarrhea 78 (16%) 35 (45%) 43 (55%) <0.001 2.61 (1.58−4.32)
 Nausea/Vomiting 41 (9%) 25 (61%) 16 (39%) <0.001 4.94 (2.54,9.6)
 Asymptomatic 253 (53%) 32 (13%) 221 (87%) <0.001 0.19 (0.12−0.3)
Approximate duration of symptoms in days (IQR)a 7 (3−14) 14 (5−21) 5 (3−7) <0.001
 <5 days 94 (20%) 26 (28%) 68 (72%) Ref
 6−14 days 77 (16%) 37 (48%) 40 (52%) 0.006 2.4 (1.2−4.5)
 >14 days 47 (10%) 37 (79%) 10 (21%) <0.001 9.6 (4.2−22.2)



Type of PPE usedd
 N95 only 76 (16%) 19 (25%) 57 (75%) 0.300 0.87 (0.5,1.54)
 Surgical mask only 109 (23%) 39 (36%) 70 (64%) 0.020 1.7 (1.08,2.69)
 N95 and surgical mask 361 (75%) 90 (25%) 271 (75%) 0.050 0.64 (0.41,1)
 Face shield and goggles 329 (69%) 77 (23%) 252 (77%) 0.004 0.55 (0.36,0.84)
 None 2 (0.4%) 1 (50%) 1 (50%) 0.470 2.69 (0.17,43.2)



Nature of work
 Physician 157 (33%) 39 (25%) 118 (75%) Ref
 Nurse 142 (30%) 40 (28%) 102 (72%) 0.510 1.18 (0.7−1.9)
 Ancillary service 72 (15%) 20 (28%) 52 (72%) 0.600 1.1 (0.62−2.1)
 Others 107 (22%) 31 (29%) 76 (71%) 0.450 1.2 (0.71−2.1)



Health care worker exposuree
 High and moderate 65 (14%) 25 (38%) 40 (62%) 0.710 1.84 (1.06,3.18)
 Low 413 (86%) 105 (25 %) 309 (75%)
Community exposuref 119 (25%) 44 (37%) 75 (63%) 0.005 1.86 (1.19−2.9)



Location of residence
 Manhattan 79 (17%) 22 (28%) 57 (72%) Ref
 Bronx 154 (32%) 41 (27%) 113 (73%) 0.840 0.94 (0.51−1.7)
 Brooklyn 20 (4%) 7 (35%) 13 (65%) 0.530 1.39 (0.49−3.95)
 Queens 39 (8%) 12 (31%) 27 (69%) 0.740 1.15 (0.49−2.66)
 Long island 19 (4%) 6 (32%) 13 (68%) 0.740 1.19 (0.40−3.5)
 Upstate NY 11 (2%) 2 (18%) 9 (82%) 0.500 0.57 (0.11−2.87)
 New Jersey 47 (10%) 9 (19%) 38 (81%) 0.270 0.61 (0.25−1.47)
 Westchester county NY 24 (5%) 7 (29%) 17 (71%) 0.900 1.06 (0.38−2.92)
 Rest of the country 85 (18%) 24 (28%) 61 (72%) 0.900 1.01 (0.51−2.01)



Travel historyg
 Domestic (High risk) 26 (5%) 3 (12%) 23 (88%) 0.040 0.18 (0.03−0.96)
 International (High risk) 19 (4%) 5 (26%) 14 (74%) 0.340 1.9 (0.38−9.44)
a

IQR-Interquartile Range.

b

Public Transport includes: Subway, Taxi or Bus.

c

BCG Vaccine received in childhood.

d

PPE: Personal Protective Equipment.

e

High-Risk HCW defined as: HCP who had prolonged close contact with patients with COVID-19 not wearing a facemask while the HCP nose and mouth were exposed to material potentially infectious with the virus causing COVID-19 OR Being present in the room for procedures that generate aerosols or during which respiratory secretions are poorly controlled when the HCP’s eyes, nose, or mouth were not protected. Moderate Risk HCW was defined as: HCP who had prolonged close contact with patients with COVID-19 who were not wearing a facemask while the HCP nose and mouth were exposed to material potentially infectious with the virus causing COVID-19. Low-Risk HCW was defined as: Brief interactions with patients with COVID-19 or prolonged close contact with patients who were wearing a facemask for source control while the HCP was wearing a facemask or respirator.

f

Community Exposure defined as: Individual had close contact (<6 feet) for ≥15 min to a person with COVID-19 who had symptoms or a Person who has tested positive for COVID-19 but were asymptomatic.

g

High-Risk Domestic locations include: California and Washington state. High-Risk International locations include: China, South Korea, Iran, Italy, and Spain.