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. Author manuscript; available in PMC: 2021 Apr 20.
Published in final edited form as: Adv Funct Mater. 2020 Feb 24;30(16):1908788. doi: 10.1002/adfm.201908788

Table 2.

The summarized IC50 of GSNO, PTX, pPTX/pCD-pSH and pPTX/pCD-pSNO NPs in LS174T, EL4, B16F10 and E0771 cancer cell lines.

PTX IC50 (μM) −SNO IC50 (μM)
LS174T EL4 B16F10 E0771 LS174T EL4 B16F10 E0771
GSNO - - - - 56.3±15.8 16.5±7.0 16.9±4.1 20.6±0.6
Free PTX 0.38±0.10 0.68±0.08 0.42±0.19 0.58±0.11 - - - -
pPTX/pCD-pSH 0.19±0.04 0.46±0.13 0.19±0.12 0.19±0.03 - - - -
pPTX/pCD-pSNO 0.11±0.05 0.27±0.10 0.09±0.01 0.15±0.06 (15.4±7.2) x10−3 (39.4±13.7) x10−3 (12.7±0.5) x10−3 (22.1±8.2) x10−3