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The summarized combination index of pPTX/pCD-pSNO compared to the mixture of free PTX and free GSNO, or the mixture of pPTX/pCD-pSH NPs and free GSNO.
| combination index at IC50 (CI50) | vs. Free PTX+Free GSNO | vs. PTX/SH-NP+Free GSNO | ||||||
|---|---|---|---|---|---|---|---|---|
| LS174T | EL4 | B16F10 | E0771 | LS174T | EL4 | B16F10 | E0771 | |
| pPTX/pCD-pSNO | 0.28 | 0.40 | 0.22 | 0.26 | 0.57 | 0.60 | 0.47 | 0.81 |
