Table 3.

Fully adjusted^a logistic regression models including odds ratio (OR) and 95% confidence interval (CI)(Model 1) with outcome of total serum prostate specific antigen (PSA) >4 ng/mL and linear regression with$\mathit{\beta }$ coefficient and 95% CI (Model 2) with outcome of total serum (continuous), stratified by age (y); Chicago 2013–2018.

Participant Characteristics	Model 1		Model 2
	OR	(95% CI)	$\beta$	(95% CI)
Age
Cigarette smoking history	40 to <55 years
Never	1.00	(Reference)	0.00	(Reference)
0 to 1 pack-year	1.16	(0.29 to 4.72)	−0.11	(−0.49 to 0.28)
>1 pack-year	1.76	(0.18 to 16.8)	0.00	(−0.62 to 0.61)
Current marijuana use
No	1.00	(Reference)	0.00	(Reference)
Yes	1.67	(0.47 to 5.92)	0.15	(−0.21 to 0.52)
Other current tobacco useb
No	1.00	(Reference)	0.00	(Reference)
Yes	2.32	(0.56 to 9.59)	0.29	(−0.19 to 0.77)
Total	497
Age	≥55 years
Cigarette smoking history
Never	1.00	(Reference)	0.00	(Reference)
0 to 1 pack-year	2.26	(0.76 to 6.73)	0.33	(−0.37 to 1.04)
>1 pack-year	5.09	(1.57 to 16.6)**	0.77	(−0.09 to 1.63)
Current marijuana use
No	1.00	(Reference)	0.00	(Reference)
Yes	0.27	(0.08 to 0.96)*	−0.69	(−1.43 to 0.04)
Other current tobacco useb
No	1.00	(Reference)	0.00	(Reference)
Yes	2.38	(0.76 to 7.52)	1.20	(0.20 to 2.19)*
Total	431
Age	All ages
Cigarette smoking history
Never	1.00	(Reference)	0.00	(Reference)
0 to 1 pack-year	1.86	(0.84 to 4.12)	0.12	(−0.25 to 0.49)
>1 pack-year	4.34	(1.73 to 10.9)**	0.52	(0.01 to 1.04)*
Current marijuana use
No	1.00	(Reference)	0.00	(Reference)
Yes	0.55	(0.25 to 1.22)	−0.19	(−0.56 to 0.17)
Other current tobacco useb
No	1.00	(Reference)	0.00	(Reference)
Yes	1.99	(0.91 to 4.38)	0.63	(0.13 to 1.12)
Total	928

^aAdjusted for age (continuous), marital status, individual and neighborhood socioeconomic status, self-reported health, previous cancer diagnosis, body mass index, hypertension medication (yes/no), health insurance type, timing of last prostate specific antigen test, timing of last prostate exam such as digital rectal exam, and visits to a doctor in the last 12 months (quintiles).

^bOther tobacco use includes current regular use of E-cigarettes, cigars, pipes, snuff, chewing tobacco, and hookah.

^*p-value < 0.05

^**p-value <0.01