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. 2020 Oct 15;11:5214. doi: 10.1038/s41467-020-19055-7

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© The Author(s) 2020, corrected publication 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 3 — a Schematic of the rapid neutralization assay. b Summary of neutralizing titers as measured by PRNT and SARS-CoV-2-Nluc neutralization (Nluc-NT) assay. Serum specimens 1–21 were from COVID-19 patients with confirmed prior RT-PCR diagnosis. Serum specimens 22–30 were from non-COVID-19 individuals. c Representative neutralizing curves of the Nluc-NT assay. Two independent experiments are shown. The four-parameter dose–response curve was fitted using the nonlinear regression method and NT₅₀s were calculated in the software Prism 8. d Correlation analysis between the Nluc-NT₅₀ and PRNT₅₀ values. The Pearson correlation coefficient and two-tailed p value from a linear regression analysis are shown.