Table 4.

Changes in plasma acyl carnitine derivatives with respect to time following surgery

Acyl carnitine	P (adjusted)	Fold change Day 1	Fold change Day 3	Fold change Day 7
Adipoylcarnitine (C6‐DC)	1.4E‐06	5.04	4.52	3.25
Suberoylcarnitine (C8‐DC)	2.7E‐04	3.99	4.40	3.33
3,4‐Methyleneheptanoylcarnitine	4.2E‐02	3.49	1.72	1.38
Decanoylcarnitine (C10)	2.3E‐03	1.95	1.84	2.49
Octanoylcarnitine (C8)	9.0E‐03	1.84	1.48	1.85
Octadecenedioylcarnitine (C18:1‐DC)*	1.7E‐02	1.76	1.96	1.70
Hexanoylcarnitine (C6)	7.0E‐03	1.75	1.55	1.52
cis‐4‐Decenoylcarnitine (C10:1)	2.0E‐02	1.65	1.48	1.83
Pimeloylcarnitine/3‐Methyladipoylcarnitine (C7‐DC)	2.0E‐02	1.57	2.65	2.92
Octadecanedioylcarnitine (C18‐DC)*	1.8E‐03	1.53	1.76	1.91
Laurylcarnitine (C12)	1.1E‐03	1.30	1.49	2.13
Myristoleoylcarnitine (C14:1)*	1.9E‐03	0.88	1.21	1.59
Behenoylcarnitine (C22)*	3.1E‐06	0.78	1.47	2.31
Myristoylcarnitine (C14)	6.1E‐07	0.67	1.06	1.33
Lignoceroylcarnitine (C24)*	2.1E‐11	0.67	0.95	1.52
Cerotoylcarnitine (C26)*	7.3E‐07	0.67	1.04	1.50
Ximenoylcarnitine (C26:1)*	2.2E‐12	0.62	1.18	2.10
Margaroylcarnitine (C17)*	9.6E‐08	0.57	0.79	1.14
Nervonoylcarnitine (C24:1)*	4.1E‐15	0.53	1.16	1.89
Palmitoleoylcarnitine (C16:1)*	3.4E‐06	0.51	0.77	1.12
Oleoylcarnitine (C18:1)	9.0E‐12	0.47	0.80	1.10
Palmitoylcarnitine (C16)	2.8E‐11	0.46	0.79	1.07
Eicosenoylcarnitine (C20:1)*	1.9E‐07	0.45	1.43	1.87
Linoleoylcarnitine (C18:2)*	1.7E‐07	0.45	0.61	0.94
Stearoylcarnitine (C18)	9.4E‐13	0.44	0.84	1.13
Dihomo‐linoleoylcarnitine (C20:2)*	1.7E‐06	0.41	0.72	1.13
Arachidoylcarnitine (C20)*	2.6E‐10	0.41	0.72	1.15
Linolenoylcarnitine (C18:3)*	4.0E‐09	0.39	0.54	0.86
Arachidonoylcarnitine (C20:4)	1.5E‐10	0.32	0.44	0.85

A two‐way ANOVA was performed on log‐transformed data in Metaboanalyst as described in Methods. Fold change was calculated on unlogged data. C(x) refers to carbon chain length; DC, dicarboxylate;

^* metabolite identification by mass spectrum only.