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. Author manuscript; available in PMC: 2021 Sep 11.
Published in final edited form as: Small Methods. 2020 Jun 17;4(9):2000235. doi: 10.1002/smtd.202000235

Figure 1. Contributions of the immune system in the regulation of complex physiological processes of the different organ systems.

Figure 1.

For example, the immune cells play crucial role in the normal functioning of the CNS, heart conductivity and heart tissue repair, white/brown adipose tissues, and muscle tissue homeostasis. Alteration of the immune system results in diseases, such as fibrosis, obesity, and neurological disorders including ASD and IBS, among others. Reproduced with permission.[10] Copyright 2018, Elsevier. ASD: autism spectrum disorder, CNS: central nervous system, FAP: fibroblast activation protein, IBS: irritable bowel syndrome, WAT: white adipose tissue.