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. 2020 Oct 16;15(10):e0237643. doi: 10.1371/journal.pone.0237643

Fig 1. MitoKATP channel blocker restrains the protective effect of NaHS on maternal CS exposure-induced impairment of central chemoreception in offspring medullary slices.

Fig 1

(A) Typical recordings of hypoglossal rootlets discharges in medullary slices of the offspring. In each panel, the upper and lower lines indicate the raw (XII ENG) and integrated (∫XII ENG) activities of hypoglossal rootlets during baseline, acidification and washout, respectively; (B) comparison of basal burst frequency (BF) in different groups. Changes of BF in the (C) Control group (n = 8), (D) CS group (n = 8), (E) CS+NaHS group (n = 8), (F) CS+NaHS+5-HD group (n = 6), (G) NaHS group (n = 8) and (H) 5-HD group (n = 6); (I) comparison of maximum changes of BF of hypoglossal rootlets discharges responding to acidified perfusion among all groups. XII ENG: electroneurogram of hypoglossal rootlets, ∫XII ENG: integrated XII ENG. *P<0.05 vs. 0 min; &P<0.05 vs. Control group; #P<0.05 vs. CS group; $P<0.05 vs. CS+NaHS group.