Figure 6. NF-GMS carried hESC-CM injection dramatically decreased infarct size and increased heart function as indicated by Masson Trichrome staining.
(A), quantitative analysis (B), EF (C) and FS (D), wall thickness (E), LVIDD (F), and LVIDS (G) evaluations. (E) Rat MI hearts were analyzed 4 weeks after transplantation. N=9, *, p < 0.05, **, p < 0.01, compared with PBS group; ##, p < 0.01, #, p < 0.05, compared with CM group. NF-GMS alone had little effect whereas CM+NF-MGS transplantation led to a 60% reduction in infarct size compared to PBS control.