Figure 5. Biodistribution of the PCBP2 siRNA nanocomplex in rats with CCl4-induced liver fibrosis.
One hour after injection of the Cy5-labeled siRNA nanocomplex (1 mg siRNA/kg) via tail vein, the rats were euthanized, and major organs including the liver, spleen, kidneys, lungs, heart and muscle were harvested for fluorescence analysis. (A) Fluorescence images of the harvested organs. (B) Fluorescence intensity of the harvested organs. Results are represented as the mean ± SD (n=5).