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. 2020 Aug 18;10(2):020503. doi: 10.7189/jogh.10.020503

Table 6.

Stratified analysis of the likelihood of death among patients with respiratory system diseases infected with COVID-19 diseases

Characteristics
Pooled OR (95% CI)
P-value
Heterogeneity
Meta-regression
Type of diseases:
Chronic lung disease
3.34 (2.15-5.18)
<0.01
0.232
Chronic obstructive pulmonary disease (COPD)
2.62 (1.48-4.64)
<0.01

Pulmonary emphysema
4.69 (0.41-52.97) ++
NA

Chronic bronchitis
1.53 (0.41-5.68)++
NA

Asthma
1.01 (0.61-1.67)
0.152

Study country:
Australia
4.56 (2.47-8.44)++
NA
0.214
Italy
1.54 (0.73-3.25)
NA

China
3.46 (2.20-5.43)
<0.01

United State of America
2.11 (1.26-3.52)
<0.01

Iran
2.16 (1.05-4.45) ++
NA

Mexico
1.20 (0.54-2.68)
<0.01

Study design:
Cross-sectional
1.20 (0.54-2.68)
<0.05
0.221
Prospective cohort
2.76 (1.45-5.23)
<0.01

Retrospective cohort
2.98 (2.00-4.44)
<0.01

Adjustment factor:
Unadjusted
2.79 (1.60-4.84)
<0.01
<0.05
Adjusted
1.53 (0.96-2.46)
<0.01

Sample size:
>1134
1.88 (1.14-3.09)
<0.01
0.161
≤1134
2.97 (2.11-4.16)
<0.01

Mean age of the total sample:
≤60
3.41 (1.86-6.26)
<0.01
0.279
>60
2.32 (2.63-3.29)
<0.01

Mean age of death sample:
≤70
4.22 (2.44-7.30)
0.209
0.055
>70 2.16 (1.57-2.99) <0.01