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THOC2 inhibition reduced melanoma cell proliferation. (a, b) Relative expression of THOC2 in A375 and M14 cells transfected with siRNAs or NC was measured by RT-qPCR and western blot. (c) MTT assays showed that THOC2 inhibition reduced melanoma cell proliferative ability in vitro. (d) Flow cytometric analysis showed that THOC2 inhibition increased apoptosis of melanoma cells. *P < 0.05.
