Skip to main content
. 2020 Jan 10;17(11):1680–1692. doi: 10.1080/15476286.2019.1710405

Table 3.

Influencing on chromatin remodelling complex.

lncRNAs Cancer type Functions and phenotype References
LncTCF7 Liver cancer Recruits SWI/SNF complex to the promoter of TCF7, triggers Wnt signalling pathway to increase CSC self-renewal and cause cancer recurrence. [96]
SChLAP1 Pprostate cancer Interacts with SWI/SNF complex, represses the expression of PTEN gene and promotes the process of tumorigenesis in prostate cancer cells. [97]
lncHand2-AS1 Liver cancer Recruits INO80 chromatin remodelling complex to the promoter region of BMP signalling receptor BMPR1A, promotes the expression of BMPR1A, activates BMP signalling pathway, and maintains self-renewal of liver cancer stem cells. [104]