Table 3.
lncRNAs | Cancer type | Functions and phenotype | References |
---|---|---|---|
LncTCF7 | Liver cancer | Recruits SWI/SNF complex to the promoter of TCF7, triggers Wnt signalling pathway to increase CSC self-renewal and cause cancer recurrence. | [96] |
SChLAP1 | Pprostate cancer | Interacts with SWI/SNF complex, represses the expression of PTEN gene and promotes the process of tumorigenesis in prostate cancer cells. | [97] |
lncHand2-AS1 | Liver cancer | Recruits INO80 chromatin remodelling complex to the promoter region of BMP signalling receptor BMPR1A, promotes the expression of BMPR1A, activates BMP signalling pathway, and maintains self-renewal of liver cancer stem cells. | [104] |