Table 6.
lncRNAs | Cancer type | Functions and phenotype | References |
---|---|---|---|
ARHGAP5-AS1 | Gastric cancer | ARHGAP5-AS1 interacts with ARHGAP5 promoter directly to promote the transcriptional expression of ARHGAP5. It promotes autophagy activity and allows cell survival in vitro and tumorigenesis in vivo. | [129] |
LEADeR (MIR205HG) |
Prostate cancer | Directly binds to the Alu elements, leads to a transcriptional repression of the target gene possibly via buffering the activity of IRF1 on the promoter. | [136] |