Figure 4.

Mechanistic comparison of inflammatory processes in patients with COVID-19 versus ARDS, sepsis, and CAR T cell-induced CRS

ARDS=acute respiratory distress syndrome. CAR T cell-induced CRS=chimeric antigen receptor T cell-induced cytokine release syndrome. CRP=C-reactive protein. DAMPs=damage-associated molecular patterns. IFN=interferon. IL=interleukin. LDH=lactate dehydrogenase. PAMPs=pathogen-associated molecular patterns. PCT=procalcitonin. ROS=reactive oxygen species. SARS-CoV-2=severe acute respiratory syndrome coronavirus 2. ssRNA=single-stranded RNA. vWF=von Willebrand factor. *Effector function measured by ex vivo functional assays.