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. 2020 Oct 12;12:9999–10010. doi: 10.2147/CMAR.S261979

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© 2020 Wang et al.

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The effect of MALAT1 knockdown on DDP-resistant OC cells. (A) MALAT1 expression was measured in SKOV3/DDP and OVCAR3/DDP cells transfected with si-NC, si-MALAT1#1, or si-MALAT1#2, respectively (n=3). (B) IC₅₀ of cisplatin was examined (n=3). (C and D) MTT assay was performed to assess cell proliferation (n=3). (E and F) Flow cytometry analysis was performed to detect cell apoptosis (n=3). (G–J) Cell migratory (G and H) and invasive (I and J) abilities were determined using transwell assays (magnification × 100) (n=3). *P<0.05.