Figure 8. FNR as a global regulator.

FNR is known to be upregulated in anaerobic growth, and here we found it to regulate a suite of six genes. In aerobic growth conditions, the putative FNR sites are weakened. (A) Information footprints for the six regulated promoters. Activator binding regions are highlighted in green, repressor-binding regions in red, and RNAP binding regions in blue. (B) Sequence logos for the FNR-binding sites displayed in (A). The DNA binding preference of the six sites are shown to be similar from their sequence logos. Numeric values for the binding locations can be found in Figure 8—source data 1.