Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Sep 21;9:e55308. doi: 10.7554/eLife.55308

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2020, Ireland et al

This article is distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use and redistribution provided that the original author and source are credited.

PMC Copyright notice

Figure 9. — (A) Here, the information footprint of the arcA promoter is displayed along with the energy matrix describing the discovered FNR-binding site. (B) Intra-operon regulation of fdhE by both FNR and ArcA. The information footprint of fdhE is displayed. The discovered sites for FNR and ArcA are highlighted and the energy matrix for ArcA is displayed. A TOMTOM (Gupta et al., 2007) search of the binding motif found that ArcA was the most likely candidate for the transcription factor. The displayed information footprint from a knockout of ArcA demonstrates that the binding signature of the site, and its associated RNAP site, are no longer determinants of gene expression. (C) Sequence logos for FNR generated from both the sites cataloged in RegulonDB, as well as the discovered sites regulating arcA and fdhE. (D) Sequence logos for ArcA from sites contained in RegulonDB and the ArcA site regulating fdhE. Numeric values for the binding locations can be found in Figure 9—source data 1.

Figure 9—source data 1. Data for information footprints, energy matrices, and PWMs in Figure 9B.

elife-55308-fig9-data1.xlsx^{(18.2KB, xlsx)}