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. 2020 Oct 13;33(2):108249. doi: 10.1016/j.celrep.2020.108249

Figure 6.

Figure 6

Kinetic Profiling of KSHV Proteins

(A) Schematic overview of the proteomic analysis of cells with latent versus lytic infection at 36, 48, and 60 h upon KSHV reactivation.

(B) Hierarchical cluster analysis of all viral proteins quantified. The heatmap diagram shows temporal and PAA-sensitivity profiles for 62 KSHV ORFs. Rows and columns represent individual viral ORFs and experimental samples, respectively.

(C–G) Average temporal and PAA-sensitivity profiles of viral proteins in clusters 1–5. Protein abundance is calculated as a fraction of maximum TMT reporter ion intensity.

See also Figures S6 and S7.