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. 2020 Oct 17;159(3):933–948. doi: 10.1016/j.chest.2020.09.275

Figure 1.

Figure 1

Consort diagram showing selection of patients, inclusion criteria, and exclusion criteria applied to form the final cohort of 3,098 patients. Exclusion criteria included receiving any of the immunomodulatory drugs before the diagnosis of cytokine storm, age younger than 18 years, having received all three study drugs, having received the combination of anakinra and tocilizumab, or missing clinically relevant covariates. Three thousand ninety-eight patients remained in the final analysis. CCS = coronavirus disease 2019 cytokine storm; COVID-19 = coronavirus disease 2019; CRP = C-reactive protein; LDH = lactate dehydrogenase; PCR = polymerase chain reaction.