Fig. 1.

The expression of SNORA71B was higher in relative high brain metastatic BC tissues and cells, and Kaplan–Meier survival curve analysis of the prognostic significance of high and low expression of that in breast cancer. a SNORA71B expression was high in BCBM tissues compared with BC tissues through GSE100534 datasets analysis. b SNORA71B expression was high in breast tumor tissues compared with normal breast tissues via SNORic datasets analysis. c, d Low SNORA71B expression was correlated with better Overall Survival (OS) and Post-Progression Survival (PPS) in breast cancer (n = 626, n = 173). e The receiver operating characteristics (ROC) curves of SNORA71B in breast cancer patients. Notes: The area under the ROC curve was 0.634, (P value = 7.4e-07). f The expression level of SNORA71B in the high (MDA-MB-231BM) and low (MDA-MB-231, SKBRS, MDA-MB-468, and MCF-7) BM BC cells and normal breast cells (MCF10A) using qRT-PCR analysis. The data represent three repeated experiments, presented as mean ± SD. **P < 0.05, **P < 0.01, ***P < 0.001