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. 2020 Apr 22;47(12):2753–2764. doi: 10.1007/s00259-020-04814-x

Table 1.

Clinical and baseline demographic characteristics of all participants

Cohort Group Sex (M/F) Age (years) Education (years) MMSE score APOE ε4 positive rate
Cohort A

Training dataset

(n = 255)

sMCI (n = 166) 90/76 71.2 ± 7.81 16.1 ± 2.62 28.4 ± 1.51 45.2%
pMCI (n = 89) 52/37 73.2 ± 7.56 16.4 ± 2.47 26.9 ± 1.54 64.1%
P value 0.52a 0.045b 0.36c < 0.001b 0.0041a

Test dataset

(n = 255)

sMCI (n = 166) 85/81 70.6 ± 6.81 16.1 ± 2.64 28.4 ± 1.53 34.3%
pMCI (n = 89) 50/39 74.1 ± 6.21 15.5 ± 2.79 27.1 ± 2.03 73.0%
P value 0.45a 0.01b 0.11c <0.001b <0.001a
Cohort B HC (n = 50) 24/26 74.6 ± 3.17 15.8 ± 2.53 29.1 ± 1.01 28%
AD (n = 50) 28/22 74.8 ± 2.75 15.7 ± 2.64 23.1 ± 2.23 74%
P value 0.55a 0.71b 0.87c < 0.001b < 0.001a

Pa, the chi-square test; Pb, the two-sample t test; Pc, the Wilcoxon rank-sum test. sMCI, stable MCI; pMCI, progressive MCI; MMSE, mini-mental state examination; APOE ε4 positive rate, positive or negative for the presence of at least one ε4 allele

Data are given as mean ± SD