Table 1.
Baseline characteristics of patients undergoing spirometry with bronchodilator response and BCT at the diagnostic center (N = 645).
| Variable | Results | Missing data |
|---|---|---|
| Age, mean ± SD (range) | 43.24 ± 14.87 (16–76) years | n = 13 |
| Age of onset, mean ± SD (range) | 33.3 ± 18.38 (0–71) years | |
| Sex, n (%) | ||
| Male | 231 (36%) | |
| Female | 414 (64%) | |
| BMI, mean ± SD (range) | 27.8 ± 5.52 (16–53) kg/m2 | n = 1 |
| Smoking | ||
| Never | 359 (56%) | |
| Previous | 195 (30%) | |
| Current | 91 (14%) | |
| Family history (asthma), n (%) | ||
| Positive | 278 (44%) | |
| Negative | 291 (46%) | |
| Unknown | 76 (10%) | |
| ACQ total, mean ± SD (range) | 1.37 ± 0.90 (0–4.83) | |
| FEV1 in L, mean ± SD (range) | ||
| Pretest, L | 3.08 ± 0.807 L (1.49–5.96 L) | n = 12 |
| % predicted | 95.85% ± 13.04% (67.5%–141.6%) | n = 13 |
| Post-test, L | 3.18 ± 0.84 L (1.62–6.17 L) | n = 1 |
| % predicted | 99.02% ± 13.14% (66–139%) | n = 1 |
| FEV1/FVC %, mean ± SD (range) | ||
| Pre-BD | 78.49 ± 7.80 (54.70–100) | n = 12 |
| Post-BD | 81.61 ± 7.49 (54.45–100) | |
| FEV1/FVC ≤ 70%, n (%) | ||
| Pre-BD | 85 (13%) | |
| Post-BD | 43 (7%) | |
| Reversibility %, mean ± SD (range) | 3.55% ± 4.0% | n = 12 |
| 10–12% | 16 | |
| ≥12% | 4 | |
| Reversibility in mL, in case of ≥12% | 372 ± 49.92 (320–440) | |
| ICS use, n (%) | ||
| ICS mono | 84 (13.0%) | |
| ICS/LABA | 133 (20.6%) | |
| ICS total | 217 (33.6%) | |
| Antihistamine use, n (%) | ||
| Oral | 81 (12.5%) | |
| Nasal | 55 (8.5%) | |
| Ocular | 3 (0.5%) | |
| Self-reported allergy, n (%) | ||
| Pets | 76 (12%) | |
| Food | 26 (4%) | |
| Hay fever/seasonal | 141 (22%) | |
| Wheezing (ACQ5), n (%) | ||
| Yes | 392 (61%) | |
| No | 253 (39%) | |
| AB or prednisone ≥1 course last year, n (%) | ||
| No | 449 (70%) | |
| Yes | 191 (30%) | |
| Working diagnosis from spirometry, n (%) | ||
| Probable asthma | 363 (56%) | |
| Possible asthma (unclear) | 221 (34%) | |
| Asthma | 27 (4%) | |
| COPD | 14 (2%) | |
| Asthma/COPD | 8 (1%) | |
| No airflow obstruction | 6 (1%) | |
| Possible restriction | 3 (0.5%) | |
| Poor curve | 3 (0.5%) | |
AB antibiotics, ACQ Asthma Control Questionnaire, BD bronchodilator, BMI body mass index, COPD chronic obstructive pulmonary disease, FEV1 forced expiratory volume in 1 s, FVC forced vital capacity, ICS inhalation corticosteroid, LABA long-acting beta agonist, SD standard deviation.