Table 3.
Comparison of Cardiovascular Event Incidence and Regression Model Results
| HRU Rates, per patient-mo |
Incidence Rate Ratio (95% CI)a |
|||
|---|---|---|---|---|
| Hyporesponder (N = 43,316) | Normoresponder (N = 67,403) | Unadjusted Model | Adjusted Model | |
| Hospitalizations related to: | ||||
| Heart failure | 0.0992 | 0.0590 | 1.68 (1.64-1.72) | 1.39 (1.36-1.43) |
| Myocardial infarction | 0.0135 | 0.0101 | 1.34 (1.27-1.42) | 1.24 (1.17-1.31) |
| Stroke | 0.0144 | 0.0106 | 1.36 (1.30-1.43) | 1.28 (1.22-1.34) |
| Thromboembolic event | 0.0139 | 0.0084 | 1.66 (1.58-1.75) | 1.44 (1.36-1.51) |
| Mortalityb | 25.27% | 22.59% | ||
Note: P < 0.001 for all comparisons in both models.
Abbreviations:CI, confidence interval; HRU, health care resource use.
a
Hyporesponders versus normoresponders.
b
Proportion of patients who died during the study period.