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. 2020 Sep 20;38:100766. doi: 10.1016/j.nmni.2020.100766

Table 2.

Comparative efficacy of Saccharomyces boulardii in the management of acute diarrhoea

Outcome variables SB group Non-SB group p value
Mean duration of diarrhoea post-treatment (days)
 Mean (SD) 3.0 (1.0) 4.4 (1.1)
 Median (IQR) 3 (2–4) 4 (4–5) <0.05
Change in mean body weight (kg)
 Mean (SD) 0.3 (0.4) –0.4 (1.8)
 Median (IQR) 0.3 (0.02–0.4) 0 (–0.2 to 0.1) <0.05
Mean frequency of stools post-treatment as per reported on the follow-up visit (loose stools/day)
 Mean (SD) 1.7 (0.6) 2.5 (1.5)
 Median (IQR) 2 (1–2) 2 (2–2.3) <0.05
Dehydration status, n (%) 80 (50) 80 (50)
No dehydration, n, mean duration of diarrhoea post-treatment (SD) 22, 2.6 (0.9) 58, 4.3 (0.2) <0.05
Some dehydration, n, mean duration of diarrhoea post-treatment (SD) 58, 3.2 (0.9) 22, 4.7 (0.7)
Total, n, mean (SD) 80, 3.0 (1.1) 80, 4.4 (1.1)

Abbreviations: IQR, interquartile range; SB, Saccharomyces boulardii; SD, standard deviation.