Table 2.
Longitudinal mean trend of clinical and adherence measures.
| Measures | Baseline, mean (SD) | 8 weeks, mean (SD) | 6 months, mean (SD) | 12 months, mean (SD) | Significancea | ||||||||
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F test (df) | P value (adj) | ||||||
| Primary outcome measure (Depression symptom severity)b | 13.7 (5.0) | 7.2 (5.1) | 7.0 (5.4) | 7.2 (5.6) | 121.6 (3) | <.001 | |||||||
| Secondary outcome measures | |||||||||||||
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Anxiety symptom severityc | 10.3 (4.7) | 6.4 (4.7) | 6.2 (4.8) | 6.0 (5.4) | 50.4 (3) | <.001 | ||||||
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Work and social functioningd | 20.2 (8.0) | 15.2 (9.4) | 13.7 (9.7) | 13.3 (10.5) | 29.1 (3) | <.001 | ||||||
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Resiliencee | 22.2 (6.6) | 25.6 6.1) | 26.1 (6.3) | 26.5 (6.7) | 28.9 (3) | <.001 | ||||||
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Suicidal ideationf (score ≥1), n (%) | 72 (39.8) | 13 (12.2) | 15 (16.5) | 16 (17.2) | 48.9 (3)g | <.001h | ||||||
| Adherence measures | |||||||||||||
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Logins (cumulative counts) | N/Ai | 8.9 (9.6) | 11.1 (13.3) | 11.7 (14.3) | N/A | N/A | ||||||
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Page views (cumulative counts) | N/A | 66.3 (70.4) | 80.9 (89.1) | 84.8 (93.5) | N/A | N/A | ||||||
| Lessons completed (cumulative counts) | N/A | 7.7 (7.9) | 8.9 (9.1) | 9.2 (9.3) | N/A | N/A | |||||||
aP value was associated with the test (F test, Type 3 tests of fixed effects) of the overall time period (week) difference. P values adjusted by the Bonferroni method (adj) are shown.
bPatient Health Questionnaire-9 (PHQ-9) score range = 0 to 27.
cGeneralized Anxiety Disorder Scale-7 (GAD-7) score range = 0 to 21.
dWork and Social Adjustment Scale (WSAS) score range = 0 to 40.
eConnor-Davidson Resilience Scale-10 (CD-RISC-10) score range = 0 to 40.
fPHQ-9 Item 9, Suicidal Ideation, score range = 0 to 3.
gChi-square statistic, χ2 (degrees of freedom).
hP value was associated with the test (χ2, Type 3 generalized estimating equations analysis) of the overall time period (week) difference. P value adjusted by the Bonferroni method (adj) is shown.
iN/A: not applicable.