Fig. 2.
The time of half completion, t1/2, is plotted on logarithmic scale as a function of peptide concentration for the serine mutants in comparison with the WT Aβ42 in 20 mM sodium phosphate and 200 µM EDTA at pH 8.0. Error bars represent the SD of three replicates as shown in Fig. 3, and the data from the three replicates are averaged. (A) The mutants of the (18+21) hydrophobic patch are shown in comparison with the quadruple mutant peptide and the WT peptide, and (B) compares the mutants of the (40+42) hydrophobic patch.