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. Author manuscript; available in PMC: 2020 Oct 17.
Published in final edited form as: Lancet Neurol. 2011 Aug 3;10(9):806–818. doi: 10.1016/S1474-4422(11)70155-7

Figure3: Receiver-operating-characteristic curves for different biomarkers (continuous values) of muscle-manifesting respiratory chain deficiencies in adults and children.

Figure3:

Areas under the curves are: 0·97 (95% CI 0·94–0·99) for FGF-21 in serum; 0·90 (0·84–0·96) for lactate; 0·80 (0·70–0·93) for pyruvate; 0·90 (0·82–0·98) for L:P; and 0·63 (0·51–0·74) for CK. L:P=ratio of lactate to pyruvate. CK=creatine kinase.