Table 3.
Chronological order of publications and details of Waorani’s research
| No. | Institution's country | Author | Year | Number of population | Communities of origin | Study method | Material | Origin of samples | Ethics committee approval | Informed consent |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | USA | James W. Larrick et al. [28] | 1978 | 600 Waorani | ND | Observational Epidemiological study | Surveys | – | ND | ND |
| 2 | USA | Jonathan E. Kaplan et al. [29] | 1980 | 293 Waorani | Tiweno, Tzapino, Gabaro | Basic research, analytical procedures | Serologic test, skin test data and stool examination | Primary | ND | ND |
| 3 | USA | Jonathan E. Kaplan et al. [30] | 1980 | 227 Waorani | Tiweno, Tzapino, Bai's, Gareno | Basic research, analytical procedures | Serologic test, skin test data and stool examination | Primary | ND | ND |
| 4 | UK | Theakston RD, et al. [31] | 1981 | 223 Waorani | ND | Basic research, analytical procedures | Serologic test | Primary | ND | ND |
| 5 | USA | James W. Larrick et al. [32] | 1983 | 227 Waorani | ND | Basic research, analytical procedures | Serologic test, skin test data and stool examination | Primary | ND | ND |
| 6 | USA | E.Wade Davis et al. [33] | 1983 | ND Waorani | ND | Observational Epidemiological study | Descriptive evaluation | – | ND | ND |
| 7 | UK | Theakston RD et al. [34] | 1983 | 7 Waorani | ND | Applied Basic research—Animal study | Inoculation of human antibodies against the snake venoms | Primary | ND | ND |
| 8 | USA | James W. Larrick et al. [35] | 1985 | 231 Waorani | Tzapino, Bai's, Tiweno, Gabaro | Basic research, analytical procedures | Serologic test | Primary | ND | ND |
| 9 | USA | C. Edward Buckley et al. [36] | 1985 |
229 Waorani Other foreign groups |
ND | Basic research, analytical procedures | Serologic test and skin test data | Primary | ND | ND |
| 10 | USA | James W. Larrick et al. [37] | 1987 | 70 Waorani | ND | Basic research, analytical procedures | Serologic test | Primary | ND | ND |
| 11 | USA | David I. Watkins et al. [38] | 1992 | 17 Waorani | ND | Basic research, analytical procedures | Serologic test | Primary | ND | ND |
| 12 | BRASIL | Fabrício R. Santos et al. [19] | 1996 | 1 Waorani | ND | Basic research, analytical procedures | DNA sample | Secondary—Coriell Institute of Medical Research | ND | ND |
| 13 | USA | Evan E. Eichler et al. [20] | 1996 | 1 Waorani | ND | Basic research, analytical procedures | Arrayed X-chromosome library | Secondary—Lawrence Livermore National Laboratory | ND | ND |
| 14 | GERMANY | Colm O’Huigin et al. [39] | 1997 | 6 Waorani | ND | Basic research, analytical procedures | Serologic test | Primary | ND | ND |
| 15 | BRASIL | Fabrício R. Santos et al. [21] | 1999 | ND Waorani | ND | Basic research, analytical procedures | DNA sample | Secondary—National Institute of General Medical Science | ND | ND |
| 16 | USA | Michael A. Kron et al. [40] | 2000 |
31 Dicaro Waorani 8 Non-Dicaro Waorani 16 Quichua |
Dicaro | Basic research, analytical procedures | Serologic test | Primary | ND | Acquired |
| 17 | ECUADOR | Stephen R. Manock et al. [41] | 2000 | 173 Waorani | 15 Waorani Villages | Basic research, analytical procedures | Serologic test | Primary | Leadership of ONHAE | ND |
| 18 | BRASIL | Francisco M. Salzano [42] | 2002 | ND Waorani | ND | Systematic review | – | – | Local and National ethics committees | ND |
| 19 | USA | Lizhi Yu et al. [22] | 2003 | 1 Waorani | ND | Basic research, analytical procedures | DNA sample | Secondary—Coriell Institute | ND | ND |
| 20 | JAPAN | Yasuhiro Go et al. [23] | 2005 | 1 Waorani | ND | Basic research, analytical procedures | DNA sample | Secondary—Coriell Institute | ND | ND |
| 21 | MEXICO | Maria Mercedes Meza et al. [24] | 2005 | 1 Waorani | ND | Basic research, analytical procedures | DNA sample | Secondary—Coriell Institute | ND | ND |
| 22 | USA | Eray Tuzun et al. [25] | 2005 | 1 Waorani | ND | Basic research, analytical procedures | DNA sample | Secondary—Coriell Institute Cell Repository | ND | ND |
| 23 | ESPAÑA | Fabricio Gonzales [43] | 2006 | 40 Waorani | ND | Basic research, analytical procedures | Serologic test | Primary | ND | Acquired |
| 24 | USA | Nicholas J. Marini et al. [26] | 2008 | ND Waorani | ND | Basic research, analytical procedures | DNA sample | Secondary—Coriell Institute Cell Repository | ND | ND |
| 25 | USA | Stephen Beckerman et al. [44] | 2009 | 121 Waorani | ND | Observational Epidemiological study | Surveys | – | Institutional Review Boards of Pennsylvania State University and the University of Connecticut | Acquired |
| 26 | ESPAÑA | Fabricio Gonzales et al. [45] | 2009 |
35 Waorani 102 Mestizos 102 Kichwa 102 Afro- Ecuadorian |
ND | Basic research, analytical procedures | Serologic test | Primary | Metropolitan Hospital | Acquired |
| 27 | ESPAÑA | M. Baeta et al. [1] | 2009 | 111 Waorani | Toñampare, Bameno | Basic research, analytical procedures | Saliva swab samples | Primary | ND | ND |
| 28 | USA | William Kuang-Yao Pan et al. [46] | 2010 |
221 Quichua 99 Shuar 78 Huaorani 50 Cofan 31 Secoya |
ND | Observational Epidemiological study | Surveys | – | University of North Carolina at Chapel Hill | ND |
| 29 | ESPAÑA | Luis Gomez—Perez et al. [47] | 2011 | 36 Waorani | ND | Basic research, analytical procedures | Serologic test | Primary | University of the Basque Country | Acquired |
| 30 | GERMANY | Maria Geppert et al. [48] | 2011 | 65 Waorani | ND | Basic research, analytical procedures | Buccal swab samples | Primary | Approved by an ethical commission not specified | Acquired |
| 31 | ESPAÑA | S Cardoso et al. [49] | 2012 | 36 Waorani | ND | Basic research, analytical procedures | Serologic test | Primary | Institutional Review Board from UPV/EHU | Acquired |
| 32 | ESPAÑA | Luis Gomez—Perez et al. [50] | 2013 | 36 Waorani Other foreign group | ND | Basic research, analytical procedures | Serologic test | Primary | Institutional Review Board from UPV/EHU | Acquired |
| 33 | GERMANY | Lutz Roewer et al. [51] | 2013 |
40 Waorani Fifty different ethnic groups |
ND | Basic research, analytical procedures | Buccal swabs, liquid saliva and capillary blood | Primary | Institutional review board of the Institute of Legal Medicine and Forensic Sciences, Berlin | Acquired |
| 34 | USA | Douglas S.London et al. [52] | 2014 |
16 Waorani 63 Kiwchas |
Kawymeno | Basic research, analytical procedures | Stool samples | Primary | ND | ND |
| 35 | USA | Douglas S.London et al. [53] | 2015 |
121 Waorani 312 Kiwchas |
Kawymeno | Observational Epidemiological study | Surveys | – | Institutional Review Board at Arizona State University | Acquired |
| 36 | UK | Massimo Mezzavilla et al. [54] | 2015 |
22 Waorani 9 Kiwchas |
ND | Basic research, analytical procedures | Serologic test | Primary | Institute of Legal Medicine and Forensic Sciences, Germany | Acquired |
| 37 | GERMANY | Maria Geppert et al. [27] | 2015 |
20 Waorani 24 Kiwcha |
ND | Basic research, analytical procedures | DNA sample | Secondary—obtained of other studies | ND | ND |
| 38 | ECUADOR | Edy Quizhpe et al. [55] | 2016 | 199 Waorani | 22 Waorani Villages | Observational Epidemiological study | Surveys | – | ND | ND |
The table only described the indigenous communities belong to Ecuador. In the origin of the samples: primary refers to obtaining samples directly from the population and secondary refers to obtaining genetic samples from gene banks belonging to international institutions
ND not described