Table 1.
Site Sample Characteristics For Each Diagnostic Group.
Discovery Sample | Replication Sample | |||
---|---|---|---|---|
Healthy Individuals N = 52 |
Patients with Bipolar Disorder N = 44 |
Healthy Individuals N = 41 |
Patients with Bipolar Disorder N = 78 |
|
Male Sex (n,%) | 28 (53.8) | 29 (65.9) | 13 (31.7) | 26 (33.3) |
Age (mean, years) | 29.8 (8.3) | 27.6 (8.3) | 33.2 (11.8) | 34.2 (12.6) |
IQ (mean) | 115.2 (16.6) | 103.0 (17.9) | 104.1 (19.7) | 106.0 (17.1) |
BPRS Total Score (mean) | 24.2 (0.4) | 46.3 (19.8) | 25.5 (3.9) | 32.6 (8.7) |
Psychotic Symptoms (n,%) | – | 44 (100) | – | 21 (26.9) |
Unmedicated (n,%) | – | 4 (9.3) | – | 15 (19.2) |
Lithium (n,%) | – | 18 (41.9) | – | 11 (14.1) |
Antipsychotics (n,%) | – | 34 (79.1) | – | 24 (30.8) |
Daily Antipsychotic Dose (CPZE) | – | 275.9 (339.3) | – | 92.2 (224.5) |
Continuous variables are shown as mean (standard deviation); BPRS: Brief Psychiatric Rating Scale; CPZE: Chlorpromazine equivalents.