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. 2020 Sep 12;7(10):ofaa425. doi: 10.1093/ofid/ofaa425

Table 2. .

Association of HIV Infection With sICAM-1 and sVCAM-1 Adjusted for Demographic, and CVD Risk Factors Plus Markers of Intestinal Barrier Dysfunction and Monocyte Activation

Fully Adjusteda Fully Adjusted + I-FABPb Fully Adjusted + sCD14b
% Estimate (95% CI) % Estimate (95% CI) % Estimate (95% CI)
sICAM-1
HIV- Reference Reference Reference
HIV+ 49 (33 to 67)** 42 (26 to 60)** 18 (5 to 33)*
sVCAM-1
HIV- Reference Reference Reference
HIV+ 30 (14 to 48)** 23 (8 to 41)* 0 (–13 to 15)

Table 2 shows the results of a multivariable linear regression analysis that assessed the associations between HIV serostatus with sVCAM-1 and sICAM-1. “% Estimate” inidcates percent differences.

Abbreviations: CVD, cardiovascular disease; HDL, high-density lipoprotein; I-FABP, intestinal fatty acid-binding protein; sCD14, cluster of differentiation 14; sICAM-1, soluble intercellular cell adhesion molecule–1; sVCAM-1, soluble vascular cell adhesion molecule–1.

*P < .05; **P < .001.

aThe models are adjusted for age, sex, and CVD risk factors (fasting glucose levels, systolic blood pressure, body mass index, smoking and alcohol consumption status, triglycerides, and HDL cholesterol).

bThe models are adjusted for age, sex, CVD risk factors, sCD14 or I-FABP.