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. 2020 Sep 12;7(10):ofaa425. doi: 10.1093/ofid/ofaa425

Table 3. .

Associations Between sCD14 and Endothelial Activation Markers by HIV Status

sICAM-1 sVCAM-1
β (95% CI) P interaction a β (95% CI) P interaction a
Minimally adjustedb .30 .20
ALL 0.33 (0.24 to 0.39) 0.34 (0.27 to 0.42)
HIV+ d 0.26 (0.15 to 0.39)*** 0.43 (0.29 to 0.59)***
HIV- 0.34 (0.24 to 0.44)*** 0.29 (0.19 to 0.39)***
.38 .12
Fully adjustedc ALL 0.32 (0.25 to 0.40) 0.38 (0.29 to 0.46)
HIV+ d 0.28 (0.16 to 0.41)*** 0.46 (0.32 to 0.62)***
HIV- 0.35 (0.26 to 0.44)*** 0.31 (0.21 to 0.40)***

Results are presented as β coefficients and 95% CIs. Interpret the coefficient as the percent increase/decrease in sICAM-1 or sVCAM-1 for every 1% increase in the biomarker of interest.

*P < .05; **P < .01; ***P < .001.

a P interaction sICAM-1 or sVCAM-1 (HIV status and biomarker).

bMinimally adjusted for age, sex, and HIV serostatus (for the entire population).

cFully adjusted for age, sex, and CVD risk factors (fasting glucose levels, systolic BP, body mass index, smoking and alcohol consumption status, triglycerides, and HDL cholesterol).

dAnalyses were further adjusted for current and nadir CD4 T-cell count and ART duration.