Table 1.
Characteristics of the study population.
| Infants without EOS (n = 141,213) | Infants with EOS (n = 1197) | Total study population (n = 142,410) | |
|---|---|---|---|
| Gestational age, weeks | 39 [38, 40] | 39 [38, 40] | 39 [38, 40] |
| Birth weight, g | 3347 [3000, 3709] | 3 379 [3047, 3660] | 3 348 [3000, 3708] |
| Male | 57.8% | 55.8% | 57.8% |
| Race/ethnicity | |||
| White | 47.6% | 45.2% | 47.6% |
| Black | 16.8% | 15.8% | 16.8% |
| Hispanic | 28.4% | 31.2% | 28.5% |
| Other | 7.2% | 7.8% | 7.2% |
| Apgar score at 5 min | |||
| 0–3 | 2.0% | 1.5% | 2.0% |
| 4–6 | 6.6% | 6.6% | 6.6% |
| 7–10 | 91.4% | 91.8% | 91.4% |
| Maternal age at birth, years | 28 [23, 32] | 27 [22, 31] | 28 [23, 32] |
| Cesarean section | 47.3% | 35.4% | 47.2% |
| Positive maternal GBS colonization status | 22.2% | 17.4% | 22.1% |
| Prolonged rupture of membranes | 9.3% | 14.5% | 9.3% |
| Prenatal antibiotic exposure | 41.1% | 32.0% | 41.1% |
| Prenatal steroid exposure | 1.4% | 1.5% | 1.4% |
| Ventilator on or before day of culture | 5.6% | 8.9% | 5.6% |
| Vasopressor treatment on or before day of culture | 0.9% | 3.3% | 0.9% |
| Died | 0.2% | 0.8% | 0.2% |
| Discharge year | |||
| 2011 | 15.8% | 17.4% | 15.8% |
| 2012 | 16.1% | 15.7% | 16.1% |
| 2013 | 16.3% | 16.0% | 16.3% |
| 2014 | 17.6% | 17.0% | 17.6% |
| 2015 | 17.6% | 16.4% | 17.5% |
| 2016 | 16.7% | 17.5% | 16.7% |
Values presented as % or median [p25–p75].
EOS early-onset sepsis, GBS group B Streptococcus, NIPPV noninvasive positive pressure ventilation, CPAP continuous positive airway pressure, NC nasal cannula.