Table 3.

Association between factors and risk of EOS on multivariable logistic regression analysis.

Variable	Adjusted OR	95% CI	p value
Gestational age (reference: 40 weeks)
37	0.89	(0.71–1.10)	0.28
38	1.09	(0.92–1.31)	0.32
39	0.95	(0.81–1.13)	0.59
41	1.11	(0.83–1.47)	0.49
Small for gestational age	0.70	(0.54–0.90)	0.006
Male	0.98	(0.87–1.10)	0.70
Race/ethnicity (reference: White)
Black	1.05	(0.86–1.28)	0.67
Hispanic	1.13	(0.97–1.32)	0.11
Other	1.15	(0.91–1.47)	0.24
Apgar score at 5 min (reference: 7–10)
0–3	0.37	(0.20–0.69)	0.002
4–6	0.81	(0.61–1.07)	0.13
Maternal age at birth (reference: 20–29)
≤19 years	1.35	(1.13–1.62)	0.001
30–39 years	0.87	(0.74–1.01)	0.06
≥40 years	0.72	(0.46–1.13)	0.15
Cesarean section	0.66	(0.57–0.76)	<0.001
GBS colonization status (reference: negative)
Positive	0.83	(0.70–0.99)	0.04
Missing or unknown	0.73	(0.58–0.92)	0.008
Prolonged rupture of the membranes	1.71	(1.42–2.05)	<0.001
Prenatal care	0.90	(0.69–1.18)	0.45
Prenatal antibiotic exposure	0.70	(0.61–0.81)	<0.001
Prenatal steroid exposure	1.10	(0.66–1.82)	0.72
Vasopressor treatment on or before day of culture	3.64	(2.51–5.29)	<0.001
Ventilator on or before day of culture	1.58	(1.19–2.10)	0.001
Discharge year (reference: 2011)
2012	0.88	(0.71–1.11)	0.28
2013	0.92	(0.74–1.14)	0.45
2014	0.90	(0.71–1.13)	0.35
2015	0.86	(0.70–1.05)	0.14
2016	0.98	(0.79–1.21)	0.85

CI confidence interval, EOS early-onset sepsis, GBS group B Streptococcus, OR odds ratio.