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. 2020 Oct 17;10(1):187–200. doi: 10.1007/s40121-020-00357-8
Severe pneumonia caused by multidrug-resistant Acinetobacter baumannii (MDR-AB) remains a difficult-to-treat infection.
Considering the poor lung penetration of most antibiotics, the choice of the better antibiotic regimen is debated.
During the study period, 180 cases of hospital-acquired pneumonia, including ventilator-associated pneumonia, caused by MDR-AB strains were observed.
A fosfomycin-containing regimen was associated with 30-day survival.
This real-life clinical experience provides useful suggestions to clinicians, showing the use of different antibiotic regimens with a predominant role for fosfomycin.