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. Author manuscript; available in PMC: 2020 Nov 11.
Published in final edited form as: Nat Metab. 2020 May 11;2(5):432–446. doi: 10.1038/s42255-020-0199-4

Extended Data Fig. 4. Expression of urea cycle enzymes and related pathways in FACS-purified human β-cells subjected to transcriptomic analyses.

Extended Data Fig. 4

RNAseq analysis of urea cycle enzymes and related pathways in sorted human β-cells and negative-sorted islet cells relative to whole islets. Read counts as RPKM (reads per kilobase per million mapped reads) are normalized to whole islet PKRM to assess enrichment. All urea cycle related enzymes and transporters are enriched (>1) in the β-cell fraction compared to whole islets and the negative-sorted cells.