Table 3A.
Comparison of nosocomial and community-acquired PIV-3.
| Hospital-acquired | Community-acquired | P value | ||
|---|---|---|---|---|
| n = 104 (24.3%) | n = 324 (75.7%) | |||
| Study population | ||||
| Age [years] | [median (IQR)] | 58 (29.25-64.75) | 3 (1-61) | <0.0005 |
| Female gender | [%(n/total)] | 41.3 (43/104) | 42.6 (138/324) | 0.823 |
| Comorbidities/risk factors | ||||
| History of malignant neoplasia | [%(n/total)] | 75.0 (78/104) | 19.8 (64/324) | <0.0005 |
| Blood malignancy | [%(n/total)] | 69.2 (72/104) | 14.2 (46/324) | <0.0005 |
| Solid cancer | [%(n/total)] | 14.4 (15/104) | 7.4 (24/324) | 0.031 |
| Immunosuppression | [%(n/total)] | 73.1 (76/104) | 20.1 (65/324) | <0.0005 |
| Chronic renal failure | [%(n/total)] | 22.1 (23/104) | 15.4 (50/324) | 0.115 |
| Cardiac insufficiency | [%(n/total)] | 11.5 (12/104) | 14.2 (46/324) | 0.491 |
| Asthma | [%(n/total)] | 2.9 (3/104) | 6.8 (22/324) | 0.140 |
| COPD | [%(n/total)] | 3.8 (4/104) | 14.5 (47/324) | 0.004 |
| Obesity (BMI >30 kg/m²) | [%(n/total)] | 19.4 (13/67) | 6.2 (14/227) | 0.001 |
| Clinical presentation and features | ||||
| Leucocytes on admission [exp 9/l] | [median (IQR)] | 6.8 (4.2-9.3) | 10.3 (6.9-14.3) | <0.0005 |
| Length of hospitalization [days] | [median (IQR)] | 36.5 (22-68.75) | 7 (4-12.75) | <0.0005 |
| Admission to ICU | [%(n/total)] | 27.9 (29/104) | 21.9 (71/324) | 0.211 |
| Length of stay in ICU [days] | [median (IQR)] | 28 (5-70) | 5 (3-12.5) | 0.001 |
| Acute respiratory distress syndrome | [%(n/total)] | 1.0 (1/104) | 1.9 (6/324) | 0.533 |
| Ventilation | [%(n/total)] | 18.4 (19/103) | 10.2 (33/324) | 0.026 |
| Invasive | [%(n/total)] | 15.5 (16/103) | 8.3 (27/324) | 0.034 |
| Noninvasive | [%(n/total)] | 2.9 (3/103) | 1.9 /6/324) | 0.514 |
| Viral co-infection | [%(n/total)] | 23.1 (24/104) | 31.2 (101/324) | 0.114 |
| Death (<30 days after discharge) | [%(n/total)] | 8.7 (9/104) | 4.6 (15/324) | 0.121 |
COPD = chronic obstructive pulmonary disease; PIV-3 = parainfluenza virus type 3. Analyzed categories are displayed on the column to the left and either given as frequencies [%] or median and interquartile range [median(IQR)]. (n/total) indicates the respective cases of the total amount of available data. A comparison was done for the whole study period and a P value <0.05 was considered significant (highlighted in bold).