Table II.
Cell population | Sham (n=5) | CLP + Vehicle (n=8) | CLP + PKCδ Inhibitor (n=6) |
---|---|---|---|
CD68+CD86+(% of CD45+ cells) | 48.6 ± 9.74 | 17.8 ± 1.32 *** | 22.7 ± 2.15 *§ |
CD163+(% of CD68+CD86+ cells) | 19.2 ± 2.33 | 9.59 ± 1.96 ** | 6.62 ± 0.71 *** |
CCR2+(% of CD68+CD86+CD163+ cells) | 2.68 ± 0.63 | 9.75 ± 2.25 * | 6.27 ± 1.79 |
CD163-(% of CD68+CD86+ cells) | 73.5 ± 3.14 | 86.5 ± 2.45 ** | 91.1 ± 1.27 *** |
CCR2+ (% of CD68+CD86+CD163- cells) |
2.32 ± 0.37 | 6.53 ± 1.90 | 4.25 ± 1.48 |
p < 0.05 relative to Sham
p < 0.01 relative to Sham
p < 0.001 relative to Sham
p < 0.05 relative to CLP + vehicle