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Downregulation of PVT1 repressed tumor growth. (A) Tumor volume was measured every 5 d. (B) Weight of the resected tumor was examined after the mice were killed. (C) The mRNA levels of PVT1, miR-515-5p and PIK3CA in NPC cells infected with sh-PVT1 or sh-Control were checked by qRT-PCR. (D) The protein level of PIK3CA in transfected NPC cells was measured by Western blot. *P < 0.05.
