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. 2020 Oct 13;12:10055–10065. doi: 10.2147/CMAR.S252916

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© 2020 Han et al.

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The association between miR-1283 and CHD1. (A) The target sites of miR-1283 and CHD1 were searched via TargetScan. (B and C) Luciferase activity was measured in T98G and U251 cells transfected with CHD1 3ʹUTR-WT or CHD1 3ʹUTR-MUT. (D) CHD1 expression in glioma tissues was predicted via GEPIA. (E–H) The mRNA and protein levels of CHD1 were measured in glioma cells and tissues. (I) The linear correlation between the levels of CHD1 and miR-1283 were analyzed. (J) The expression of miR-1283 was measured in T98G and U251 cells transfected with miR-NC or miR-1283. (K and L) The mRNA and protein levels of CHD1 were detected in T98G and U251 cells transfected with miR-NC or miR-1283. *P<0.05.