Table 3.

Clusters of Keywords in Web of Science

Cluster 1	Diagnosis, individual, ethic, family, ethical issue, gene, alzheimer, genetic, ethical aspect, genomic, newborn screening, whole exome sequencing, whole genome sequencing, ethical challenge, precision medicine, schizophrenia, incidental finding
Cluster 2	Cancer, chemotherapy, tumor, woman, case report, informed consent, female, malignancy, ethical concern, ethical approval, pregnancy, rarity, trisomy, poor prognosis, newborn
Cluster 3	Rare disease, orphan drug, decision, policy, decision-making, expert, survey genetic testing, ethical dilemma, orphan disease, pharmaceutical industry, family member, clinical practice, patient advocacy organization, new drug
Cluster 4	Disorder, registry, biobank, clinical research, drug development, placebo, ethical consideration, enzyme replacement therapy, rare condition, drug administration
Cluster 5	Child, participant, consent, hypertension, questionnaire, adolescent, caregiver, severe malaria
Cluster 6	Parent, relationship, expectation, interview, investigator, rare disease research